diff --git a/config/discourse_defaults.conf b/config/discourse_defaults.conf
index b2d96e4bde0..ce589d63b84 100644
--- a/config/discourse_defaults.conf
+++ b/config/discourse_defaults.conf
@@ -225,6 +225,7 @@ s3_cdn_url =
 s3_endpoint =
 s3_http_continue_timeout =
 s3_install_cors_rule =
+s3_enable_transfer_acceleration =
 
 # Optionally, specify a separate CDN to be used for static JS assets stored on S3
 s3_asset_cdn_url =
diff --git a/config/site_settings.yml b/config/site_settings.yml
index cc79179ab49..75e5784e6a0 100644
--- a/config/site_settings.yml
+++ b/config/site_settings.yml
@@ -1462,6 +1462,9 @@ files:
   enable_s3_uploads:
     default: false
     client: true
+  enable_s3_transfer_acceleration:
+    default: false
+    hidden: true
   s3_use_iam_profile:
     default: false
   s3_access_key_id:
diff --git a/lib/file_store/s3_store.rb b/lib/file_store/s3_store.rb
index 34f14dc9399..d89f3955ea7 100644
--- a/lib/file_store/s3_store.rb
+++ b/lib/file_store/s3_store.rb
@@ -25,6 +25,7 @@ module FileStore
         S3Helper.new(
           s3_bucket,
           Rails.configuration.multisite ? multisite_tombstone_prefix : TOMBSTONE_PREFIX,
+          use_accelerate_endpoint: SiteSetting.enable_s3_transfer_acceleration,
         )
     end
 
diff --git a/lib/s3_helper.rb b/lib/s3_helper.rb
index 450dc25d777..93c9ca28841 100644
--- a/lib/s3_helper.rb
+++ b/lib/s3_helper.rb
@@ -47,6 +47,15 @@ class S3Helper
     setting_klass = use_db_s3_config ? SiteSetting : GlobalSetting
     options = S3Helper.s3_options(setting_klass)
     options[:client] = s3_client if s3_client.present?
+    use_accelerate_endpoint =
+      (
+        if use_db_s3_config
+          SiteSetting.enable_s3_transfer_acceleration
+        else
+          GlobalSetting.s3_enable_transfer_acceleration
+        end
+      )
+    options[:use_accelerate_endpoint] = !for_backup && use_accelerate_endpoint
 
     bucket =
       if for_backup
@@ -349,7 +358,12 @@ class S3Helper
   def presigned_url(key, method:, expires_in: S3Helper::UPLOAD_URL_EXPIRES_AFTER_SECONDS, opts: {})
     Aws::S3::Presigner.new(client: s3_client).presigned_url(
       method,
-      { bucket: s3_bucket_name, key: key, expires_in: expires_in }.merge(opts),
+      {
+        bucket: s3_bucket_name,
+        key: key,
+        expires_in: expires_in,
+        use_accelerate_endpoint: @s3_options[:use_accelerate_endpoint],
+      }.merge(opts),
     )
   end
 
@@ -362,7 +376,12 @@ class S3Helper
   )
     Aws::S3::Presigner.new(client: s3_client).presigned_request(
       method,
-      { bucket: s3_bucket_name, key: key, expires_in: expires_in }.merge(opts),
+      {
+        bucket: s3_bucket_name,
+        key: key,
+        expires_in: expires_in,
+        use_accelerate_endpoint: @s3_options[:use_accelerate_endpoint],
+      }.merge(opts),
     )
   end
 
diff --git a/spec/requests/uploads_controller_spec.rb b/spec/requests/uploads_controller_spec.rb
index 0c8e037e86a..daed9c6b818 100644
--- a/spec/requests/uploads_controller_spec.rb
+++ b/spec/requests/uploads_controller_spec.rb
@@ -780,6 +780,29 @@ RSpec.describe UploadsController do
         )
       end
 
+      context "when enable_s3_transfer_acceleration is true" do
+        before { SiteSetting.enable_s3_transfer_acceleration = true }
+
+        it "uses the s3-accelerate endpoint for presigned URLs" do
+          post "/uploads/generate-presigned-put.json",
+               **{
+                 params: {
+                   file_name: "test.png",
+                   file_size: 1024,
+                   type: "card_background",
+                   metadata: {
+                     "sha1-checksum" => "testing",
+                     "blah" => "wontbeincluded",
+                   },
+                 },
+               }
+          expect(response.status).to eq(200)
+
+          result = response.parsed_body
+          expect(result["url"]).to include("s3-accelerate")
+        end
+      end
+
       describe "rate limiting" do
         before { RateLimiter.enable }
 
@@ -1045,7 +1068,7 @@ RSpec.describe UploadsController do
         XML
         stub_request(
           :get,
-          "https://s3-upload-bucket.s3.us-west-1.amazonaws.com/#{external_upload_stub.key}?max-parts=1&uploadId=#{mock_multipart_upload_id}",
+          "https://s3-upload-bucket.#{SiteSetting.enable_s3_transfer_acceleration ? "s3-accelerate" : "s3.us-west-1"}.amazonaws.com/#{external_upload_stub.key}?max-parts=1&uploadId=#{mock_multipart_upload_id}",
         ).to_return({ status: 200, body: list_multipart_result })
       end
 
@@ -1129,6 +1152,24 @@ RSpec.describe UploadsController do
         )
       end
 
+      context "when enable_s3_transfer_acceleration is true" do
+        before { SiteSetting.enable_s3_transfer_acceleration = true }
+
+        it "uses the s3-accelerate endpoint for presigned URLs" do
+          stub_list_multipart_request
+          post "/uploads/batch-presign-multipart-parts.json",
+               params: {
+                 unique_identifier: external_upload_stub.unique_identifier,
+                 part_numbers: [2, 3, 4],
+               }
+
+          expect(response.status).to eq(200)
+          result = response.parsed_body
+          expect(result["presigned_urls"].keys).to eq(%w[2 3 4])
+          expect(result["presigned_urls"]["2"]).to include("s3-accelerate")
+        end
+      end
+
       describe "rate limiting" do
         before { RateLimiter.enable }
 
@@ -1173,7 +1214,7 @@ RSpec.describe UploadsController do
 
   describe "#complete_multipart" do
     let(:upload_base_url) do
-      "https://#{SiteSetting.s3_upload_bucket}.s3.#{SiteSetting.s3_region}.amazonaws.com"
+      "https://#{SiteSetting.s3_upload_bucket}.#{SiteSetting.enable_s3_transfer_acceleration ? "s3-accelerate" : "s3.#{SiteSetting.s3_region}"}.amazonaws.com"
     end
     let(:mock_multipart_upload_id) do
       "ibZBv_75gd9r8lH_gqXatLdxMVpAlj6CFTR.OwyF3953YdwbcQnMA2BLGn8Lx12fQNICtMw5KyteFeHw.Sjng--"
@@ -1396,7 +1437,7 @@ RSpec.describe UploadsController do
 
   describe "#abort_multipart" do
     let(:upload_base_url) do
-      "https://#{SiteSetting.s3_upload_bucket}.s3.#{SiteSetting.s3_region}.amazonaws.com"
+      "https://#{SiteSetting.s3_upload_bucket}.#{SiteSetting.enable_s3_transfer_acceleration ? "s3-accelerate" : "s3.#{SiteSetting.s3_region}"}.amazonaws.com"
     end
     let(:mock_multipart_upload_id) do
       "ibZBv_75gd9r8lH_gqXatLdxMVpAlj6CFTR.OwyF3953YdwbcQnMA2BLGn8Lx12fQNICtMw5KyteFeHw.Sjng--"