diff --git a/maxscale-system-test/CMakeLists.txt b/maxscale-system-test/CMakeLists.txt
index b8f7eabd3..e03567ef2 100644
--- a/maxscale-system-test/CMakeLists.txt
+++ b/maxscale-system-test/CMakeLists.txt
@@ -939,6 +939,9 @@ add_test_executable(mxs2300_history_pruning.cpp mxs2300_history_pruning mxs2300_
 # MXS-2326: Routing hints aren't cloned in gwbuf_clone
 add_test_executable(mxs2326_hint_clone.cpp mxs2326_hint_clone mxs2326_hint_clone LABELS readwritesplit REPL_BACKEND)
 
+# MXS-2417: Ignore persisted configs with load_persisted_configs=false
+add_test_executable(mxs2417_ignore_persisted_cnf.cpp mxs2417_ignore_persisted_cnf mxs2417_ignore_persisted_cnf LABELS REPL_BACKEND)
+
 ############################################
 # BEGIN: binlogrouter and avrorouter tests #
 ############################################
diff --git a/maxscale-system-test/cnf/maxscale.cnf.template.mxs2417_ignore_persisted_cnf b/maxscale-system-test/cnf/maxscale.cnf.template.mxs2417_ignore_persisted_cnf
new file mode 100644
index 000000000..2e90be3d1
--- /dev/null
+++ b/maxscale-system-test/cnf/maxscale.cnf.template.mxs2417_ignore_persisted_cnf
@@ -0,0 +1,3 @@
+[maxscale]
+threads=###threads###
+load_persisted_configs=false
diff --git a/maxscale-system-test/mxs2417_ignore_persisted_cnf.cpp b/maxscale-system-test/mxs2417_ignore_persisted_cnf.cpp
new file mode 100644
index 000000000..75049f0d5
--- /dev/null
+++ b/maxscale-system-test/mxs2417_ignore_persisted_cnf.cpp
@@ -0,0 +1,24 @@
+/**
+ * MXS-2417: Ignore persisted configs with load_persisted_configs=false
+ * https://jira.mariadb.org/browse/MXS-2417
+ */
+
+#include "testconnections.h"
+
+int main(int argc, char* argv[])
+{
+    TestConnections test(argc, argv);
+
+    test.tprintf("Creating a server and verifying it exists");
+    test.check_maxctrl("create server server1234 127.0.0.1 3306");
+    test.check_maxctrl("show server server1234");
+
+    test.tprintf("Restarting MaxScale");
+    test.maxscales->restart_maxscale();
+
+    test.tprintf("Creating the server again and verifying it is successful");
+    test.check_maxctrl("create server server1234 127.0.0.1 3306");
+    test.check_maxctrl("show server server1234");
+
+    return test.global_result;
+}